SCHEMBL12425017

SCHEMBL12425017

CCc1ccc(C2=C3C(=O)NC(c4cccc(C)c4)=C3C(=O)N2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
PARP10 Q53GL7 1/20 0.38
PARP11 Q9NR21 1/20 0.38
EGFR P00533 1/20 0.37
CAMK2D Q13557 1/20 0.36
PGR P06401 1/20 0.36
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36
MAPK14 Q16539 4/20 0.36
NOTUM Q6P988 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
WNT3A P56704 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815772 0.86 FYN (0.44) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL816052 0.86 FYN (0.45) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12425028 0.85 NPC1 (0.43) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12424770 0.85 PTGS2 (0.44) EGFRCTSVCTSLNOTUMTP53
SCHEMBL22431171 0.85 EGFR (0.43) EGFRCTSVCTSLNOTUMLMNA
SCHEMBL12424737 0.84 EGFR (0.48) EGFRCTSVCTSLNOTUMTP53
SCHEMBL12577694 0.82 FYN (0.41) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL7750654 0.82 GSK3B (0.43) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12640542 0.82 FYN (0.41) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL13578990 0.81 CAMK2D (0.41) FYNCLK4DYRK1BPARP10PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
EP-3902021-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH Toyo Ink SC Holdings Co., Ltd. (JP) 2021-10-27 EP disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed