Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426285 | 0.73 | TGFBR1 (0.44) | ELANE | |
| SCHEMBL12425341 | 0.70 | IDO1 (0.40) | SLC34A1PLK1ELANE | |
| SCHEMBL12426538 | 0.69 | ELANE (0.39) | SLC34A1PLK1ELANE | |
| SCHEMBL12424826 | 0.59 | TGFBR1 (0.43) | — | |
| SCHEMBL17247300 | 0.59 | CYP11B1 (0.45) | ELANEKHK | |
| SCHEMBL20074851 | 0.58 | SLC34A1 (0.51) | SLC34A1ELANE | |
| SCHEMBL17238739 | 0.57 | CYP11B1 (0.46) | PLK1KHK | |
| SCHEMBL17238734 | 0.56 | PLK1 (0.42) | PLK1KHK | |
| SCHEMBL29591487 | 0.56 | CYP11B2 (0.57) | KHK | |
| SCHEMBL13202647 | 0.56 | CYP11B2 (0.57) | KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101069-A2 | HETARYLAMINONAPHTHYRIDINES | MERCK PATENT GMBH (DE) | 2011-08-25 | — | — | WO | disclosed |