SCHEMBL12424844

SCHEMBL12424844

COc1ccc(C2=C3C(=O)NC(c4ccc(OC)c5ccccc45)=C3C(=O)N2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.46
KDR P35968 2/20 0.45
IDO1 P14902 1/20 0.44
EP300 Q09472 1/20 0.43
KAT8 Q9H7Z6 1/20 0.43
GSK3B P49841 5/20 0.43
PRKCA P17252 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 2/20 0.43
STK10 O94804 3/20 0.42
SLK Q9H2G2 3/20 0.42
PLK4 O00444 1/20 0.42
AURKA O14965 1/20 0.42
NUAK1 O60285 1/20 0.42
ABL1 P00519 1/20 0.42
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
INSR P06213 1/20 0.42
IGF1R P08069 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9042282 0.81 GSK3B (0.56) GSK3BSTK10SLK
SCHEMBL7753164 0.75 IDO1 (0.64) PRMT1IDO1EP300KAT8KMT2A
SCHEMBL12019841 0.75 IDO1 (0.64) PRMT1IDO1EP300KAT8KMT2A
SCHEMBL12019777 0.75 IDO1 (0.64) PRMT1IDO1EP300KAT8KMT2A
SCHEMBL9339235 0.74 STK10 (0.56) GSK3BSTK10SLK
SCHEMBL12424846 0.73 ACHE (0.46) KDRGSK3BPRKCAKMT2ASTK10
SCHEMBL29380721 0.73 IDO1 (0.73) IDO1EP300KAT8KMT2AKDM4E
SCHEMBL419307 0.73 IDO1 (0.73) IDO1EP300KAT8KMT2AKDM4E
SCHEMBL12424879 0.72 STK10 (0.50) KDRGSK3BSTK10SLKIGF1R
SCHEMBL12019868 0.72 IDO1 (0.59) PRMT1IDO1EP300KAT8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed