SCHEMBL12424879

SCHEMBL12424879

COc1ccc(F)cc1C1=C2C(=O)NC(c3cc(F)ccc3OC)=C2C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK10 O94804 11/20 0.50
SLK Q9H2G2 11/20 0.50
IGF1R P08069 1/20 0.44
PDGFRB P09619 1/20 0.44
KIT P10721 1/20 0.44
PDGFRA P16234 1/20 0.44
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44
KDR P35968 1/20 0.44
TEK Q02763 1/20 0.44
CCNE1 P24864 2/20 0.44
CDK2 P24941 2/20 0.44
CCNE2 O96020 1/20 0.44
CREBBP Q92793 1/20 0.43
ERN1 O75460 1/20 0.43
GSK3B P49841 3/20 0.41
MDM2 Q00987 1/20 0.40
SLC9A1 P19634 1/20 0.39
CLK2 P49760 1/20 0.39
GSK3A P49840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9042282 0.80 GSK3B (0.56) STK10SLKGSK3BCLK2GSK3A
SCHEMBL12424876 0.78 NISCH (0.41) STK10SLKPDGFRBSLC9A1
SCHEMBL12424872 0.78 CA9 (0.40)
SCHEMBL8940603 0.76 ERN1 (0.51) CREBBPERN1SLC9A1
SCHEMBL12424938 0.75 CA1 (0.38) STK10SLK
SCHEMBL12424871 0.74 TDP2 (0.46)
SCHEMBL9339235 0.73 STK10 (0.56) STK10SLKGSK3BCLK2GSK3A
SCHEMBL12424881 0.72 STK10 (0.45) STK10SLKGSK3BCLK2GSK3A
SCHEMBL12424846 0.72 ACHE (0.46) STK10SLKKDRCDK2GSK3B
SCHEMBL12424844 0.72 PRMT1 (0.46) STK10SLKIGF1RPDGFRBKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed