SCHEMBL12424862

SCHEMBL12424862

O=C1NC(c2ccccc2F)=C2C(=O)NC(c3ccccc3F)=C12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.44
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LRRK2 Q5S007 2/20 0.41
NPC1 O15118 1/20 0.41
NOTUM Q6P988 1/20 0.41
TNKS2 Q9H2K2 1/20 0.40
PTPRC P08575 1/20 0.39
PTPN1 P18031 1/20 0.39
CASP3 P42574 1/20 0.39
CASP2 P42575 1/20 0.39
CASP7 P55210 1/20 0.39
CASP6 P55212 1/20 0.39
CASP8 Q14790 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
C1R P00736 1/20 0.38
PDGFRA P16234 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23954121 0.85 ROS1 (0.43) GSK3BMEN1MAPTKMT2ANPSR1
SCHEMBL12424870 0.84 CA1 (0.38) GSK3BMEN1MAPTKMT2ANPSR1
SCHEMBL12425023 0.77 CA9 (0.41) CA1CA2CA7CA9
SCHEMBL12424872 0.76 CA9 (0.40) MEN1MAPTKMT2ALRRK2PTPN1
SCHEMBL12424871 0.76 TDP2 (0.46) MEN1MAPTKMT2APIK3CGCA1
SCHEMBL12424738 0.76 KDM4E (0.47) GSK3BPTPN1
SCHEMBL22625731 0.76 PTGS2 (0.44) GSK3BMEN1MAPTKMT2ANPSR1
SCHEMBL2301106 0.75 DAO (0.46) GSK3BLRRK2NOTUMTNKS2CASP3
SCHEMBL9340330 0.75 STK10 (0.57) GSK3B
SCHEMBL12424918 0.75 GSK3B (0.44) GSK3BMEN1MAPTKMT2ALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed