SCHEMBL12424872

SCHEMBL12424872

O=C1NC(c2cc(F)ccc2F)=C2C(=O)NC(c3cc(F)ccc3F)=C12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 3/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
PTPN1 P18031 1/20 0.40
PARP1 P09874 1/20 0.40
PARP10 Q53GL7 1/20 0.40
TGM2 P21980 1/20 0.39
FLT3 P36888 1/20 0.37
FABP6 P51161 1/20 0.37
TDP2 O95551 1/20 0.36
MEN1 O00255 1/20 0.36
PRKD3 O94806 1/20 0.36
EGFR P00533 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
MAPT P10636 1/20 0.36
SRC P12931 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424871 0.85 TDP2 (0.46) CA9CA1CA2CA7PARP1
SCHEMBL12424887 0.83 PPOX (0.50) PARP1PARP10TGM2TDP2MAPT
SCHEMBL12424972 0.83 TGM2 (0.46) TGM2FLT3TDP2MEN1EGFR
SCHEMBL12424876 0.81 NISCH (0.41) CA9CA1CA2CA7PARP1
SCHEMBL12424938 0.81 CA1 (0.38) CA9CA1CA2CA7PARP1
SCHEMBL12424869 0.81 NISCH (0.41) CA9CA1CA2CA7PARP1
SCHEMBL12424889 0.78 STK10 (0.43) CA9CA1CA2CA7PARP1
SCHEMBL12424894 0.78 GRM5 (0.37) TGM2MEN1PRKD3EGFRPRKCG
SCHEMBL12424879 0.78 STK10 (0.50)
SCHEMBL12424878 0.78 ALDH1A1 (0.44) MEN1MAPTKMT2ATDP1LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed