SCHEMBL12424874

SCHEMBL12424874

[C-]#[N+]c1cccc(C2=C3C(=O)NC(c4cc(F)c(F)c(F)c4)=C3C(=O)N2)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425032 0.84 PTGS2 (0.37) PTGS2
SCHEMBL12424802 0.82 PTGS2 (0.38) PTGS2
SCHEMBL12424860 0.79 PTGS2 (0.44) PTGS2
SCHEMBL12424859 0.79 CES2 (0.33) PTGS2
SCHEMBL12424985 0.77 NOTUM (0.41)
SCHEMBL12425048 0.77 TSHR (0.33) PTGS2
SCHEMBL12425046 0.76 PRF1 (0.35) PTGS2
SCHEMBL12509967 0.76 CHEK1 (0.43)
SCHEMBL12424875 0.75 GSK3B (0.39)
SCHEMBL12424993 0.73 MAPT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed