SCHEMBL12424993

SCHEMBL12424993

O=C1NC(c2cc(F)c(F)c(F)c2)=C2C(=O)NC(c3ccc(F)cc3)=C12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
TNKS2 Q9H2K2 1/20 0.34
TDP2 O95551 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
PRKD3 O94806 1/20 0.33
EGFR P00533 1/20 0.33
PRKCG P05129 1/20 0.33
PRKCB P05771 1/20 0.33
SRC P12931 1/20 0.33
PRKCA P17252 1/20 0.33
PRKCH P24723 1/20 0.33
PRKCI P41743 1/20 0.33
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33
PRKCZ Q05513 1/20 0.33
PRKCD Q05655 1/20 0.33
PRKD1 Q15139 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424859 0.89 CES2 (0.33) ARAKR1C3
SCHEMBL12424865 0.87 MAPT (0.41) MAPTMEN1KMT2APOLBPRKD3
SCHEMBL12424860 0.86 PTGS2 (0.44) TDP2
SCHEMBL12425046 0.86 PRF1 (0.35) TDP2PGRGRM5PDE3BPDE3A
SCHEMBL12424987 0.84 TDP2 (0.40) MAPTTDP2PDE3BPDE3A
SCHEMBL12424977 0.81
SCHEMBL12424998 0.81 MAPT (0.34) MAPTMEN1KMT2APOLBPRKD3
SCHEMBL8502944 0.80 PTGS1 (0.46) MAPTTNKS2MEN1KMT2ASTK10
SCHEMBL12424982 0.79 RXRA (0.38) MAPTTDP2KMT2AKDM4E
SCHEMBL25026520 0.79 ACHE (0.48) MAPTTNKS2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed