SCHEMBL12424965

SCHEMBL12424965

O=C1NC(c2c(F)cccc2I)=C2C(=O)NC(c3c(F)cccc3I)=C12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.41
CA9 Q16790 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
SRD5A1 P18405 1/20 0.33
TTR P02766 1/20 0.33
AKR1A1 P14550 2/20 0.33
AKR1B1 P15121 2/20 0.33
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
PARP1 P09874 2/20 0.31
PBRM1 Q86U86 1/20 0.31
DAO P14920 2/20 0.30
DDO Q99489 2/20 0.30
CA12 O43570 2/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12509905 0.91 TDP2 (0.36) TDP2CA9CA1CA2CA7
SCHEMBL12425023 0.87 CA9 (0.41) CA9CA1CA2CA7SRD5A1
SCHEMBL12425026 0.79 PBRM1 (0.45) CA9CA1CA2CA7PBRM1
SCHEMBL12425036 0.77 PTGS2 (0.40) CA9CA1CA2CA7SRD5A1
SCHEMBL12424933 0.76 STK10 (0.46)
SCHEMBL12424881 0.76 STK10 (0.45) CA9CA1CA2CA7
SCHEMBL22928191 0.73 TTR (0.37) TDP2CA9CA1CA2CA7
SCHEMBL12425018 0.73 DAO (0.31) DAO
SCHEMBL12425035 0.71 PBRM1 (0.41) PBRM1
SCHEMBL12424870 0.70 CA1 (0.38) CA9CA1CA2CA7SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed