SCHEMBL12424933

SCHEMBL12424933

O=C1NC(c2c(F)cccc2C(F)(F)F)=C2C(=O)NC(c3c(F)cccc3C(F)(F)F)=C12

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
STK10 O94804 8/20 0.46
SLK Q9H2G2 8/20 0.46
CES1 P23141 1/20 0.42
TRPA1 O75762 1/20 0.40
HTR2C P28335 9/20 0.38
HTR2B P41595 9/20 0.38
HTR2A P28223 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425023 0.84 CA9 (0.41) STK10SLKCES1HTR2CHTR2B
SCHEMBL12424930 0.77 CES1 (0.50) STK10SLKCES1
SCHEMBL12424965 0.76 TDP2 (0.41)
SCHEMBL12425026 0.76 PBRM1 (0.45) STK10SLKCES1
SCHEMBL30568365 0.75 TRPA1 (0.47) CES1TRPA1HTR2CHTR2BHTR2A
SCHEMBL12425036 0.75 PTGS2 (0.40)
SCHEMBL12424904 0.74 STK10 (0.51) STK10SLKCES1
SCHEMBL12424881 0.73 STK10 (0.45) STK10SLK
SCHEMBL12425006 0.71 STK10 (0.56) STK10SLKCES1
SCHEMBL12425018 0.71 DAO (0.31) CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed