SCHEMBL12424979

SCHEMBL12424979

O=C1NC(c2cccc(C(F)(F)F)c2)=C2C(=O)NC(c3ccc(C(F)(F)F)cc3)=C12

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.46
PARP11 Q9NR21 1/20 0.46
NOTUM Q6P988 1/20 0.43
PGR P06401 1/20 0.43
KIF11 P52732 2/20 0.42
MAPT P10636 1/20 0.42
XDH P47989 1/20 0.42
PRF1 P14222 1/20 0.41
BACE1 P56817 1/20 0.41
TDP2 O95551 1/20 0.40
IDO1 P14902 1/20 0.40
RXRA P19793 1/20 0.40
STK10 O94804 1/20 0.40
SLK Q9H2G2 1/20 0.40
ASIC3 Q9UHC3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424903 0.94 NOTUM (0.48) PARP10PARP11NOTUMPGRMAPT
SCHEMBL12425000 0.91 TP53 (0.45) PARP10PARP11NOTUMPGRKIF11
SCHEMBL12424976 0.89 NOTUM (0.44) PARP10PARP11NOTUMPGRMAPT
SCHEMBL12424858 0.87 KIF11 (0.57) KIF11BACE1TDP2
SCHEMBL12424740 0.87 TDP2 (0.45) NOTUMKIF11PRF1BACE1TDP2
SCHEMBL12424995 0.86 TDP2 (0.43) NOTUMKIF11BACE1TDP2RXRA
SCHEMBL12424991 0.84 MAPT (0.42) PARP10PARP11NOTUMPGRMAPT
SCHEMBL12424985 0.84 NOTUM (0.41) PARP10PARP11NOTUMPGRMAPT
SCHEMBL12425045 0.84 PTPN5 (0.48) PGRKIF11PRF1SLK
SCHEMBL12424997 0.81 NPY5R (0.42) NOTUMKIF11PRF1BACE1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed