SCHEMBL12424976

SCHEMBL12424976

O=C1NC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)=C2C(=O)NC(c3cccc(C(F)(F)F)c3)=C12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP11 Q9NR21 1/20 0.44
MAPT P10636 1/20 0.43
XDH P47989 1/20 0.43
PRF1 P14222 1/20 0.41
IDO1 P14902 1/20 0.41
RXRA P19793 1/20 0.41
PGR P06401 1/20 0.40
STK10 O94804 1/20 0.40
SLK Q9H2G2 1/20 0.40
SCN2A Q99250 1/20 0.40
PIM1 P11309 2/20 0.40
TTR P02766 1/20 0.40
CISD1 Q9NZ45 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
HTR2C P28335 1/20 0.39
MAOB P27338 1/20 0.39
MAP4K4 O95819 1/20 0.39
GPX4 P36969 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424903 0.95 NOTUM (0.48) NOTUMPARP10PARP11MAPTXDH
SCHEMBL12424979 0.89 PARP10 (0.46) NOTUMPARP10PARP11MAPTXDH
SCHEMBL12424970 0.88 RXRA (0.38) NOTUMRXRASTK10SLK
SCHEMBL12424985 0.88 NOTUM (0.41) NOTUMPARP10PARP11MAPTXDH
SCHEMBL12425000 0.87 TP53 (0.45) NOTUMPARP10PARP11MAPTXDH
SCHEMBL12424991 0.85 MAPT (0.42) NOTUMPARP10PARP11MAPTXDH
SCHEMBL12424995 0.84 TDP2 (0.43) NOTUMRXRAPIM1PIM2
SCHEMBL12424982 0.81 RXRA (0.38) MAPTRXRA
SCHEMBL12424992 0.79 AKR1C3 (0.33) NOTUMRXRA
SCHEMBL12424928 0.79 RXRA (0.41) NOTUMRXRAPGRSTK10SLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed