SCHEMBL12425013

SCHEMBL12425013

O=C1NC(c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)=C2C(=O)NC(c3cccc(F)c3)=C12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK10 O94804 2/20 0.41
SLK Q9H2G2 2/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
NOTUM Q6P988 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
IDO1 P14902 1/20 0.36
GRM5 P41594 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424864 0.87 NOTUM (0.44) STK10SLKALDH1A1MEN1THRB
SCHEMBL12509635 0.85 STK10 (0.36) STK10SLKALDH1A1MEN1THRB
SCHEMBL12425007 0.84 NOTUM (0.37) STK10SLKALDH1A1LMNAHPGD
SCHEMBL12425010 0.83 NOTUM (0.41) STK10SLKALDH1A1MEN1THRB
SCHEMBL12425014 0.81 PTGS2 (0.40) STK10SLKLMNAMAPTPTGS2
SCHEMBL12425011 0.76 PTGS2 (0.40) STK10SLKALDH1A1MEN1THRB
SCHEMBL814569 0.74 GSK3B (0.50) NOTUMPARP10PARP11PGR
SCHEMBL6858139 0.73 STK10 (0.46) STK10SLKALDH1A1MEN1THRB
SCHEMBL12425006 0.72 STK10 (0.56) STK10SLKALDH1A1LMNAMAPT
SCHEMBL3818590 0.72 GSK3B (0.51) STK10SLKALDH1A1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed