SCHEMBL12425006

SCHEMBL12425006

O=C1NC(c2ccccc2C(F)(F)F)=C2C(=O)NC(c3cccc(F)c3)=C12

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
STK10 O94804 10/20 0.56
SLK Q9H2G2 10/20 0.56
CES1 P23141 1/20 0.41
PDK2 Q15119 1/20 0.39
PDE3B Q13370 2/20 0.38
PDE3A Q14432 2/20 0.38
SCN9A Q15858 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424904 0.84 STK10 (0.51) STK10SLKCES1ALDH1A1
SCHEMBL12424864 0.83 NOTUM (0.44) STK10SLKALDH1A1LMNA
SCHEMBL12425010 0.78 NOTUM (0.41) STK10SLKALDH1A1LMNA
SCHEMBL12424930 0.77 CES1 (0.50) STK10SLKCES1
SCHEMBL5112656 0.76 SCN9A (0.54) STK10SLKPDK2PDE3BPDE3A
SCHEMBL12425008 0.75 STK10 (0.44) STK10SLKCES1PDK2
SCHEMBL12424926 0.74 CES1 (0.41) STK10SLKCES1MAOB
SCHEMBL12425007 0.73 NOTUM (0.37) STK10SLKALDH1A1LMNA
SCHEMBL12425005 0.73 JAK3 (0.53) STK10SLKCES1PDK2ALDH1A1
SCHEMBL12425013 0.72 STK10 (0.41) STK10SLKALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed