Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349893 | 0.86 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL13335207 | 0.86 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL12464357 | 0.86 | KCNH2 (0.41) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL17938305 | 0.84 | KCNH2 (0.38) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL28832445 | 0.84 | TRPV4 (0.44) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL17938310 | 0.82 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL16622003 | 0.82 | KCNH2 (0.36) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL20117900 | 0.82 | P2RX7 (0.35) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL20130672 | 0.82 | P2RX7 (0.35) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| Sulfoxaflor SCHEMBL18103858 | 0.81 | LGMN (0.37) | KCNH2MAP4K4PIK3CAMINK1PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351740-A1 | Insecticidal composition comprising N-substituted (6-haloalkylpyridin-3-YL)alkyl sulfoximines | Dow AgroSciences LLC (US) | 2011-08-03 | — | — | EP | disclosed |