SCHEMBL12425455

SCHEMBL12425455

CCCCCCCCSCCC(=O)Nc1ccc(NC(C)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.60
ALDH1A1 P00352 2/20 0.60
GAA P10253 2/20 0.51
ENPP2 Q13822 1/20 0.49
DGAT2 Q96PD7 1/20 0.49
PSMB11 A5LHX3 1/20 0.49
PSMA7 O14818 1/20 0.49
PSMB1 P20618 1/20 0.49
PSMA1 P25786 1/20 0.49
PSMA2 P25787 1/20 0.49
PSMA3 P25788 1/20 0.49
PSMA4 P25789 1/20 0.49
PSMB8 P28062 1/20 0.49
PSMB9 P28065 1/20 0.49
PSMA5 P28066 1/20 0.49
PSMB4 P28070 1/20 0.49
PSMB6 P28072 1/20 0.49
PSMB5 P28074 1/20 0.49
PSMB10 P40306 1/20 0.49
PSMB3 P49720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425415 0.90 MAPT (0.56) MAPTALDH1A1GAAENPP2DGAT2
SCHEMBL8589323 0.89 PSMB11 (0.63) MAPTALDH1A1GAAENPP2DGAT2
SCHEMBL13167730 0.83 MAPT (0.64) MAPTALDH1A1GAACA1CA2
SCHEMBL8624887 0.83 PSMB11 (0.71) MAPTALDH1A1GAAENPP2DGAT2
SCHEMBL13167733 0.82 MAPT (0.54) MAPTALDH1A1GAACA1CA2
SCHEMBL7748289 0.82 PSMB11 (0.55) MAPTALDH1A1GAAPSMB11PSMA7
SCHEMBL8624988 0.80 PSMB11 (0.52) MAPTALDH1A1GAAPSMB11PSMA7
SCHEMBL8623737 0.80 ALDH1A1 (0.52) MAPTALDH1A1GAAPSMB11PSMA7
SCHEMBL675018 0.78 ENPP2 (0.71) ALDH1A1ENPP2DGAT2PSMB11PSMA7
SCHEMBL9510547 0.78 ENPP2 (0.71) ALDH1A1ENPP2DGAT2PSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423685-B1 ARRAY OF PIEZOELECTRIC RESONATORS FOR THE DETECTION OF TRACE AMOUNTS OF A SUBSTANCE M S TECH LTD (IL) 2011-08-24 EP disclosed
US-7795008-B2 An organized, self-assembled monolayer (SAM) on a sensing surface of a sensor device for identifying at least one foreign material from environment; has a piezoelectric crystal element and a sensor M.S. TECH LTD. (IL) 2010-09-14 US disclosed
US-7795008-B2 An organized, self-assembled monolayer (SAM) on a sensing surface of a sensor device for identifying at least one foreign material from environment; has a piezoelectric crystal element and a sensor M.S. TECH LTD. (IL) 2010-09-14 US disclosed
US-20070117983-A1 Sensitive and selective method and device for the detection of trace amounts of a substance DAYAGI YOHAI Y 2007-05-24 US disclosed
US-20070117983-A1 Sensitive and selective method and device for the detection of trace amounts of a substance DAYAGI YOHAI Y 2007-05-24 US disclosed
US-7159463-B2 Sensitive and selective method and device for the detection of trace amounts of a substance M.S. TECH LTD. (IL) 2007-01-09 US disclosed
US-7159463-B2 Sensitive and selective method and device for the detection of trace amounts of a substance M.S. TECH LTD. (IL) 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117983-A1 Sensitive and selective method and device for the detection of trace amounts of a substance CRABP2, TMEM63A, RALA MAPT 4825/4885ALDH1A1 3157/4885GAA 4378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.