Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181376 | 0.91 | AGER (0.66) | AGERHTTNPC1MEN1GAA | |
| SCHEMBL1924100 | 0.89 | HTT (0.78) | HTTMEN1GAAMAPTKMT2A | |
| SCHEMBL11510347 | 0.88 | FFAR1 (0.63) | AGERHTTNPC1MEN1GAA | |
| SCHEMBL19534133 | 0.84 | FFAR1 (0.61) | AGERHTTNPC1MEN1GAA | |
| SCHEMBL22628164 | 0.84 | HTT (0.71) | HTTMEN1KMT2AL3MBTL1CA1 | |
| N-Benzylaniline SCHEMBL7840 | 0.84 | HTT (0.71) | HTTMEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL10756655 | 0.82 | HTT (0.69) | HTTMEN1KMT2ACA1CA2 | |
| N-Benzylaniline SCHEMBL357137 | 0.81 | HTT (0.68) | HTTMEN1KMT2AL3MBTL1CA1 | |
| N-Benzylaniline SCHEMBL3602124 | 0.81 | HTT (0.68) | HTTMEN1MAPTKMT2AL3MBTL1 | |
| N-Benzylaniline SCHEMBL2176624 | 0.81 | HTT (0.68) | HTTMEN1KMT2AL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110963927-A | Allylation method of N-benzyl aniline compound | 重庆大学 | 2020-04-07 | — | — | CN | claimed |
| CN-107129442-A | A kind of α Process for the cyanation of monoalkyl substituted aniline | 重庆大学 | 2017-09-05 | — | — | CN | claimed |
| CN-119701982-A | Application of niobium oxide supported copper catalyst in synthesis of secondary amine or derivative thereof from aromatic nitro compound and benzyl alcohol compound | 兰州大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-116102430-B | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-115745808-B | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-116102430-A | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-112409188-B | Method for synthesizing N-alkylamine | 南京理工大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-114805093-B | Preparation method of diarylamines | 暨南大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-111807971-B | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-115745808-A | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2023-03-07 | — | — | CN | disclosed |
| WO-2023016562-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |
| US-20080249175-A1 | N-Phenyloxamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-10-09 | — | — | US | disclosed |
| US-20080146572-A1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2008-06-19 | — | — | US | disclosed |
| US-7358251-B2 | N-sulfonylurea apoptosis promoters | ABBOTT LABORATORIES (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1487811-B1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-09-05 | — | — | EP | disclosed |
| US-7030115-B2 | N-sulfonylurea apoptosis promoters | ABBOTT LABORATORIES (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060074085-A1 | N-sulfonylurea apoptosis promoters | ABBVIE INC. | 2006-04-06 | — | — | US | disclosed |
| EP-1487811-A1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20030236247-A1 | N-sulfonylurea apoptosis promoters | ABBVIE INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003080586-A1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2003-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249175-A1 | N-Phenyloxamide derivatives | SERPINE1, SERPINH1, F12 | AGER 3548/4885HTT 2165/4885NPC1 1483/4885 |
| US-20080146572-A1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | BAX, BCL2, BAD | AGER 1362/4885HTT 2091/4885NPC1 1851/4885 |
| US-20060074085-A1 | N-sulfonylurea apoptosis promoters | BAX, BCL2, BAD | AGER 1362/4885HTT 2091/4885NPC1 1851/4885 |
| US-20030236247-A1 | N-sulfonylurea apoptosis promoters | BAX, BCL2, AIFM1 | AGER 1796/4885HTT 2698/4885NPC1 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.