SCHEMBL1242591

SCHEMBL1242591

C=CCCCC(CN)CC=C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170433 0.86 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13594507 0.82 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL3674102 0.81 TSHR (0.36) ALDH1A1TSHRABCC4MAPT
SCHEMBL19497196 0.80 USP2 (0.33) ALDH1A1TSHRTDP1ABCC4MAPT
SCHEMBL3122039 0.80 ALDH1A1 (0.58) ALDH1A1TSHRTDP1
SCHEMBL3116454 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTDP1
SCHEMBL3115453 0.78 TSHR (0.46) ALDH1A1TSHRTDP1
SCHEMBL10597159 0.78 ALDH1A1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL28349338 0.77 ABCC4 (0.35) ALDH1A1TSHRABCC4MAPT
SCHEMBL28507348 0.77 TSHR (0.44) ALDH1A1TSHRTDP1ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489264-A1 CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2019-05-29 EP disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
EP-2459598-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies LLC (US) 2012-06-06 EP disclosed
WO-2011016991-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 ALDH1A1 3614/4885TSHR 4812/4885TDP1 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.