SCHEMBL170433

SCHEMBL170433

C=CCCC(CN)CC=C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19302297 0.87 ALDH1A1 (0.37) ALDH1A1
SCHEMBL1242591 0.86 ALDH1A1 (0.33) ALDH1A1
SCHEMBL4901784 0.84 TSHR (0.33) ALDH1A1
SCHEMBL22031408 0.83 ALDH1A1 (0.30) ALDH1A1
SCHEMBL9307391 0.81
SCHEMBL968263 0.81
Hydrochloric Acid SCHEMBL10775962 0.78
SCHEMBL30978337 0.78 ALDH1A1 (0.39) ALDH1A1
Bromide SCHEMBL32665865 0.78 ALDH1A1 (0.39) ALDH1A1
Hydrochloric Acid SCHEMBL5167435 0.78 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125031-A2 LIPIDS AND LIPID ASSEMBLIES COMPRISING TRANSFECTION ENHANCER ELEMENTS Novosom AG (DE) 2009-12-02 EP claimed
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements CEQUENT PHARMACEUTICALS, INC. 2008-12-11 US claimed
EP-1938843-A1 Lipids and lipid assemblies comrising transfection enhancer elements Novosom AG (DE) 2008-07-02 EP claimed
WO-2008074487-A2 LIPIDS AND LIPID ASSEMBLIES COMPRISING TRANSFECTION ENHANCER ELEMENTS NOVOSOM AG (DE) 2008-06-26 WO claimed
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements MARINA BIOTECH, INC. 2008-06-19 US claimed
US-7189705-B2 Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2007-03-13 US claimed
US-6852334-B1 Cationic peg-lipids and methods of use THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2005-02-08 US claimed
US-20040241855-A1 Cationic peg-lipids and methods of use THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2004-12-02 US claimed
EP-1355670-A2 ENHANCED STABILISED PLASMID-LIPID PARTICLE-MEDIATED TRANSFECTION USING ENDOSOMAL MEMBRANE DESTABILISERS University of British Columbia (CA) 2003-10-29 EP claimed
EP-1328254-A2 LIPID FORMULATIONS FOR TARGET DELIVERY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2003-07-23 EP claimed
US-20020072121-A1 Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers UNIVERSITY OF BRITISH COLUMBIA, THE (CA) 2002-06-13 US claimed
WO-2002034236-A2 LIPID FORMULATIONS FOR TARGET DELIVERY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-05-02 WO claimed
EP-1173600-A2 CATIONIC PEG-LIPIDS AND METHODS OF USE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-01-23 EP claimed
WO-2001080900-A2 ENHANCED STABILISED PLASMID-LIPID PARTICLE-MEDIATED TRANSFECTION USING ENDOSOMAL MEMBRANE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-01 WO claimed
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
US-20240229034-A1 LIPID NANOPARTICLES AND METHODS OF USE CITY OF HOPE 2024-07-11 US disclosed
WO-2024141105-A1 LIPID COMPOUND FOR GENE DELIVERY AND LIPID NANOPARTICLE COMPRISING SAME 南京星辰智曜生物医药科技有限公司 2024-07-04 WO disclosed
WO-2000062813-A2 CATIONIC PEG-LIPIDS AND METHODS OF USE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2000-10-26 WO disclosed
EP-1041976-A1 POLYAMIDE OLIGOMERS Inex Pharmaceuticals Corp. (CA) 2000-10-11 EP disclosed
WO-1999033493-A1 POLYAMIDE OLIGOMERS INEX PHARMACEUTICALS CORPORATION (CA) 1999-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements HNRNPH3, SREBF2, PHOSPHO1 ALDH1A1 4867/4885
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements SREBF1, SREBF2, ELOVL1 ALDH1A1 3614/4885
US-20020072121-A1 Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers PLTP, SCAMP2, SCAMP3 ALDH1A1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.