SCHEMBL12425923

SCHEMBL12425923

CC1C[C@@H](Oc2ccc(C(F)(F)F)cn2)CCN1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 9/20 0.47
EPHX2 P34913 2/20 0.45
LIPG Q9Y5X9 1/20 0.43
HSD11B1 P28845 2/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.39
SCN9A Q15858 2/20 0.39
MCHR1 Q99705 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942217 0.83 LIPE (0.50) LIPEEPHX2LIPGHSD11B1SCN9A
Hydrochloric Acid SCHEMBL28660579 0.82 LIPE (0.49) LIPEEPHX2LIPGHSD11B1SCN9A
Hydrochloric Acid SCHEMBL28380497 0.82 LIPE (0.49) LIPEEPHX2LIPGHSD11B1SCN9A
SCHEMBL23708119 0.81 LIPE (0.46) LIPEEPHX2LIPGSCN9A
SCHEMBL29993956 0.81 LIPE (0.46) LIPEEPHX2LIPGSCN9A
SCHEMBL6807383 0.81 TDO2 (0.49) LIPEEPHX2LIPGHSD11B1SCN9A
SCHEMBL23703192 0.81 LIPE (0.46) LIPEEPHX2LIPGSCN9A
SCHEMBL7956516 0.81 LIPE (0.46) LIPEEPHX2LIPGSCN9A
SCHEMBL31312327 0.80 LIPE (0.46) LIPEEPHX2LIPGTSHRSMN1; SMN2
SCHEMBL15065165 0.80 LIPE (0.46) LIPEEPHX2LIPGTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999102-B2 Cross-linked cyclic amine compounds and agents for pest control NIPPON SODA CO., LTD. (JP) 2011-08-16 US disclosed
US-20090318694-A1 Cross-Linked Amine Compounds and Agents for Pest Control NIPPON SODA CO., LTD. (JP) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318694-A1 Cross-Linked Amine Compounds and Agents for Pest Control CYCS, NPY1R, CYBB LIPE 3893/4885EPHX2 860/4885LIPG 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.