Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427007 | 0.80 | — | — | |
| SCHEMBL12425501 | 0.61 | — | — | |
| SCHEMBL22308387 | 0.60 | — | — | |
| SCHEMBL17970666 | 0.59 | ALDH1A1 (0.32) | L3MBTL1 | |
| SCHEMBL6226162 | 0.59 | ALDH1A1 (0.32) | L3MBTL1 | |
| SCHEMBL12330186 | 0.58 | — | — | |
| SCHEMBL12425502 | 0.57 | — | — | |
| SCHEMBL23408386 | 0.56 | NOS1 (0.39) | — | |
| SCHEMBL13383992 | 0.56 | ACHE (0.32) | — | |
| SCHEMBL19113295 | 0.56 | ALDH1A1 (0.32) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103509-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | ACEA BIOSCIENCES INC. (US) | 2011-08-25 | — | — | WO | disclosed |