Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427691 | 0.78 | WDR5 (0.50) | PTGS2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27878863 | 0.78 | PPARG (0.48) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL3083110 | 0.77 | HPGD (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28480684 | 0.76 | HSD17B10 (0.57) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8665132 | 0.75 | HSD17B10 (0.55) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2607673 | 0.75 | TLR8 (0.50) | PTGS2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3223372 | 0.75 | BID (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28687732 | 0.75 | PTGS2 (0.44) | PTGS2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3070521 | 0.74 | HPGD (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL27675241 | 0.74 | PTGS2 (0.42) | PTGS2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| WO-2011101599-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY AROMATIC NUCLEOPHILIC SUBSTITUTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | COMT, NAA15, NUDC | PTGS2 4865/4885MEN1 223/4885KMT2A 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.