Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427569 | 0.97 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9ACNR2 | |
| SCHEMBL10283562 | 0.93 | PRKCA (0.47) | PRKCAMMP12NR1I2SCN9ACNR2 | |
| SCHEMBL803874 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL804124 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL12427734 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL803965 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL803839 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL12427636 | 0.93 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9AALDH1A1 | |
| SCHEMBL12428396 | 0.90 | PRKCA (0.42) | PRKCAMMP12NR1I2SCN9ACNR2 | |
| SCHEMBL12428400 | 0.90 | PRKCA (0.42) | PRKCAMMP12NR1I2SCN9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |