Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CCR3 | P51677 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427674 | 0.98 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12427687 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2CCR3 | |
| SCHEMBL10283573 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2CCR3 | |
| SCHEMBL803863 | 0.91 | PRKCA (0.44) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12428396 | 0.91 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12427615 | 0.90 | PRKCA (0.47) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12427737 | 0.89 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2CCR3 | |
| SCHEMBL12429265 | 0.89 | PRKCA (0.44) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12429168 | 0.89 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL12427629 | 0.88 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |