Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427629 | 0.98 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AALDH1A1 | |
| SCHEMBL12427981 | 0.96 | PRKCA (0.41) | PRKCAMMP12SCN9AKMT2AALDH1A1 | |
| SCHEMBL804085 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AKCNH2 | |
| SCHEMBL12427893 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AKCNH2 | |
| SCHEMBL12427889 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AKCNH2 | |
| SCHEMBL12427986 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AKCNH2 | |
| SCHEMBL12429142 | 0.94 | PRKCA (0.43) | PRKCAMMP12SCN9AKMT2AKCNH2 | |
| SCHEMBL12428400 | 0.91 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2CNR2 | |
| SCHEMBL803863 | 0.91 | PRKCA (0.44) | PRKCAMMP12SCN9AKMT2ANR1I2 | |
| SCHEMBL12427615 | 0.90 | PRKCA (0.47) | PRKCAMMP12SCN9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |