Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427679 | 0.94 | PRKCA (0.42) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL12427739 | 0.92 | PRKCA (0.42) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL10283563 | 0.90 | PRKCA (0.43) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL10283565 | 0.90 | CHRM2 (0.45) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL804590 | 0.89 | PRKCA (0.48) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL10283571 | 0.89 | PRKCA (0.48) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL10283570 | 0.89 | PRKCA (0.48) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL12427628 | 0.89 | PRKCA (0.48) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL804154 | 0.89 | PRKCA (0.48) | CHRM2CHRM3PRKCAMMP12SCN9A | |
| SCHEMBL12427609 | 0.88 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |