SCHEMBL12428181

SCHEMBL12428181

Cc1cccc(N2CCCc3cc(/C=C4\C(=O)N(c5ccccc5)N=C4C(=O)O)ccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.49
MEN1 O00255 10/20 0.49
GAA P10253 3/20 0.49
ALDH1A1 P00352 7/20 0.49
MAPT P10636 5/20 0.49
HTT P42858 3/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 2/20 0.49
RECQL P46063 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HKDC1 Q2TB90 1/20 0.49
PKM P14618 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
KAT8 Q9H7Z6 1/20 0.42
L3MBTL1 Q9Y468 4/20 0.40
POLB P06746 3/20 0.40
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
TDP2 O95551 1/20 0.38
MAPK1 P28482 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428170 0.95 KMT2A (0.44) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428121 0.93 KAT8 (0.45) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428191 0.90 KMT2A (0.44) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428177 0.90 KMT2A (0.43) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428192 0.90 KAT8 (0.43) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428165 0.90 KMT2A (0.44) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428185 0.89 TDP2 (0.41) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428202 0.89 KAT8 (0.43) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428176 0.89 KMT2A (0.44) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL12428142 0.88 TDP2 (0.40) KMT2AMEN1GAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 KMT2A 105/4885MEN1 251/4885GAA 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.