SCHEMBL12428142

SCHEMBL12428142

O=C(O)C1=NN(c2ccccc2)C(=O)/C1=C\c1ccc2c(c1)CCCN2c1ccc2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
ALDH1A1 P00352 5/20 0.39
MAPT P10636 5/20 0.39
KDM4E B2RXH2 3/20 0.39
RECQL P46063 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGD P15428 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MCL1 Q07820 1/20 0.37
HTT P42858 1/20 0.36
HKDC1 Q2TB90 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428201 0.93 KAT8 (0.41) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428472 0.90 KMT2A (0.49) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL14289377 0.89 KMT2A (0.42) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428169 0.89 ALDH1A1 (0.44) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428121 0.89 KAT8 (0.45) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428117 0.89 ALDH1A1 (0.44) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428136 0.89 KMT2A (0.41) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428177 0.89 KMT2A (0.43) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428164 0.89 KMT2A (0.46) TDP2KAT8KMT2AMEN1ALDH1A1
SCHEMBL12428181 0.88 KMT2A (0.49) TDP2KAT8KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 TDP2 4746/4885KAT8 1908/4885KMT2A 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.