SCHEMBL12428199

SCHEMBL12428199

Cc1ccc(N2CCCc3cc(/C=C4\C(=O)N(c5c(F)c(F)c(F)c(F)c5F)N=C4C(=O)O)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
GAA P10253 2/20 0.38
ATM Q13315 1/20 0.38
TDP2 O95551 1/20 0.37
KAT8 Q9H7Z6 3/20 0.37
KMT2A Q03164 7/20 0.36
ALDH1A1 P00352 6/20 0.36
HPGD P15428 4/20 0.36
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 3/20 0.36
RECQL P46063 2/20 0.36
MEN1 O00255 6/20 0.36
HTT P42858 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
SIRT5 Q9NXA8 2/20 0.35
TP53 P04637 1/20 0.34
SCN9A Q15858 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428192 0.92 KAT8 (0.43) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428195 0.90 L3MBTL1 (0.38) L3MBTL1GAAATMTDP2KAT8
SCHEMBL12428121 0.90 KAT8 (0.45) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428185 0.90 TDP2 (0.41) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428202 0.87 KAT8 (0.43) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428203 0.87 KMT2A (0.39) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428183 0.87 KMT2A (0.41) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL12428198 0.85 KMT2A (0.39) L3MBTL1GAATDP2KAT8KMT2A
SCHEMBL14289244 0.85 L3MBTL1 (0.35) L3MBTL1GAAATMTDP2KMT2A
SCHEMBL12428186 0.85 TDP2 (0.40) L3MBTL1GAATDP2KAT8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 L3MBTL1 2189/4885GAA 4576/4885ATM 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.