Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427956 | 0.96 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428150 | 0.96 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428144 | 0.96 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428448 | 0.95 | PRKCA (0.41) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428204 | 0.93 | PRKCA (0.40) | PRKCAMMP12SCN9AESR1NR1I2 | |
| SCHEMBL803872 | 0.92 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428410 | 0.92 | PRKCA (0.43) | PRKCAMMP12KDM2BSCN9AESR1 | |
| SCHEMBL12428104 | 0.91 | HRH3 (0.42) | PRKCAMMP12HRH3KDM4EALDH1A1 | |
| SCHEMBL12428527 | 0.91 | PRKCA (0.41) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL12427944 | 0.90 | PRKCA (0.42) | PRKCAMMP12SCN9AHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |