SCHEMBL12428342

SCHEMBL12428342

O=C(O)C1=NN(c2ccccc2)C(=O)/C1=C1\C=C(c2ccc3c(c2)CCCN3c2ccc(C(F)(F)F)cc2)CCC1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 14/20 0.49
FPR2 P25090 3/20 0.36
FPR1 P21462 1/20 0.36
KDR P35968 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CYP11B1 P15538 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428258 0.84 MAPT (0.36) SCN9AACHE
SCHEMBL14289374 0.78 ALDH1A1 (0.37) SCN9AACHE
SCHEMBL12428210 0.72 ADRB2 (0.37) ACHE
SCHEMBL12428446 0.71 MEN1 (0.42) SCN9A
SCHEMBL12428447 0.71 MEN1 (0.42) SCN9A
SCHEMBL12428463 0.71 MEN1 (0.39) SCN9AACHE
SCHEMBL12428169 0.71 ALDH1A1 (0.44) SCN9A
SCHEMBL12428117 0.71 ALDH1A1 (0.44) SCN9A
SCHEMBL12428122 0.70 KAT8 (0.41) SCN9A
SCHEMBL12428211 0.70 ADRB2 (0.38) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 SCN9A 175/4885FPR2 1206/4885FPR1 789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.