Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL772619 | 0.99 | PRKCA (0.32) | PRKCAMMP12CFTRHTR1ADRD2 | |
| SCHEMBL10283496 | 0.87 | PRKCA (0.43) | PRKCAMMP12SCN9A | |
| SCHEMBL12428671 | 0.87 | TRPM8 (0.34) | CFTRSCN9ATRPM8 | |
| Hydrochloric Acid SCHEMBL771301 | 0.87 | TRPM8 (0.34) | CFTRSCN9ATRPM8 | |
| Hydrochloric Acid SCHEMBL773221 | 0.87 | PRKCA (0.43) | PRKCAMMP12SCN9A | |
| SCHEMBL12428670 | 0.84 | FFAR4 (0.34) | CFTR | |
| Hydrochloric Acid SCHEMBL772629 | 0.84 | FFAR4 (0.34) | CFTR | |
| SCHEMBL12428599 | 0.81 | PRKCA (0.43) | PRKCAMMP12SCN9A | |
| SCHEMBL12428594 | 0.80 | PRKCA (0.43) | PRKCAMMP12SCN9A | |
| Hydrochloric Acid SCHEMBL771841 | 0.80 | PRKCA (0.43) | PRKCAMMP12SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |