Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL771301 | 0.99 | TRPM8 (0.34) | TRPM8SCN9AUSP2ALDH1A1LMNA | |
| SCHEMBL12428673 | 0.87 | PRKCA (0.32) | TRPM8SCN9ACFTR | |
| SCHEMBL12428583 | 0.87 | PRKCA (0.41) | SCN9AUSP2ALDH1A1LMNATSHR | |
| Hydrochloric Acid SCHEMBL772619 | 0.87 | PRKCA (0.32) | CFTR | |
| Hydrochloric Acid SCHEMBL771907 | 0.86 | PRKCA (0.41) | SCN9AUSP2ALDH1A1LMNATSHR | |
| SCHEMBL12428670 | 0.85 | FFAR4 (0.34) | CFTR | |
| Hydrochloric Acid SCHEMBL772629 | 0.85 | FFAR4 (0.34) | CFTR | |
| SCHEMBL12428662 | 0.84 | SCN9A (0.39) | SCN9AUSP2ALDH1A1LMNATSHR | |
| Hydrochloric Acid SCHEMBL773003 | 0.83 | SCN9A (0.38) | SCN9AUSP2ALDH1A1LMNATSHR | |
| SCHEMBL13476274 | 0.83 | ALDH1A1 (0.33) | USP2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |