SCHEMBL1242872

SCHEMBL1242872

Nc1cccc(-c2ccc(C=O)cc2)c1-c1ccc(C=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 4/20 0.44
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD5 P21918 1/20 0.42
DRD3 P35462 1/20 0.42
ADORA2A P29274 2/20 0.40
PTPRC P08575 1/20 0.40
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
BRD4 O60885 1/20 0.38
CYP2A6 P11509 2/20 0.37
PTGS1 P23219 1/20 0.36
FGR P09769 1/20 0.35
PIM1 P11309 1/20 0.35
MAOA P21397 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
DYRK1A Q13627 1/20 0.35
HIPK2 Q9H2X6 1/20 0.35
CSNK1G1 Q9HCP0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28433791 0.86 DRD1 (0.50) DRD1DRD2DRD4DRD5DRD3
SCHEMBL16174757 0.83 ALDH1A1 (0.42) DRD1ADORA2APTPRCALDH1A1HSD17B10
SCHEMBL3030804 0.82 ALDH1A1 (0.58) DRD1DRD2DRD4DRD5DRD3
SCHEMBL2931190 0.80 ALDH5A1 (0.42) ALDH1A1HSD17B10BRD4CYP2A6MAOA
SCHEMBL28409364 0.79 DRD1 (0.37) DRD1DRD2DRD4DRD5DRD3
SCHEMBL28403958 0.79 DRD1 (0.45) DRD1DRD2DRD4DRD5DRD3
Hydrochloric Acid SCHEMBL2934021 0.79 ALDH5A1 (0.41) DRD1ALDH1A1HSD17B10BRD4CYP2A6
SCHEMBL138249 0.78 ALDH1A1 (0.44) ADORA2APTPRCALDH1A1HSD17B10FGR
SCHEMBL18045125 0.76 ALDH1A1 (0.60) ADORA2APTPRCALDH1A1HSD17B10CYP2A6
SCHEMBL140573 0.76 ALDH1A1 (0.65) ADORA2APTPRCALDH1A1HSD17B10BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552325-B2 Flow battery PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2023-01-10 US disclosed
US-20210384541-A1 REDOX FLOW BATTERY AND METHOD FOR MANUFACTURING METAL ION-CONDUCTING MEMBRANE INCLUDED IN REDOX FLOW BATTERY PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2021-12-09 US disclosed
US-20210151785-A1 FLOW BATTERY PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2021-05-20 US disclosed
EP-2669339-B1 NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORP (JP) 2017-01-18 EP disclosed
US-9029434-B2 Colored photosensitive composition ADEKA CORPORATION (JP) 2015-05-12 US disclosed
US-20140332737-A1 COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2014-11-13 US disclosed
EP-2669339-A1 NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-12-04 EP disclosed
US-20130296455-A1 NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-11-07 US disclosed
US-7894118-B2 Electrochromic compound, electrochromic composition and display device RICOH COMPANY, LTD. (JP) 2011-02-22 US disclosed
US-20090231663-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION AND DISPLAY DEVICE RICOH COMPANY, LTD. (JP) 2009-09-17 US disclosed
EP-2100938-A1 Electrochromic compound, electrochromic composition and display device Ricoh Company, Limited (JP) 2009-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090231663-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION AND DISPLAY DEVICE TYR, AHR, ECH1 DRD1 140/4885DRD2 128/4885DRD4 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.