Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | FOS | P01100 | 3/20 | 0.33 |
| ▸ | JUN | P05412 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12429200 | 0.86 | TRPM8 (0.40) | TEAD2KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL12429198 | 0.84 | TEAD2 (0.43) | TEAD2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL15026115 | 0.79 | KDM4E (0.38) | TEAD2KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL12429194 | 0.77 | TEAD2 (0.36) | TEAD2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL12429213 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTNPC1HPGD | |
| SCHEMBL8694246 | 0.69 | TEAD2 (0.41) | TEAD2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8693098 | 0.68 | HTT (0.43) | TEAD2KDM4EMAPTNPC1HSD17B10 | |
| SCHEMBL8696080 | 0.68 | TEAD2 (0.41) | TEAD2KDM4EHSD17B10CYP2C19BAZ2B | |
| SCHEMBL8693715 | 0.67 | TEAD2 (0.40) | TEAD2KDM4EMAPTNPC1HPGD | |
| SCHEMBL8693052 | 0.67 | TEAD2 (0.40) | TEAD2KDM4EMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011100838-A1 | DERIVATIVES OF 1-PHENYL-1,5-DIHYDRO-BENZO[B] [1.4]DIAZEPINE-2.4-DIONE AS INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | WO | disclosed |