SCHEMBL124292

SCHEMBL124292

O=C(O)CNc1ccccc1[N+](=O)[O-]

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
KAT2B Q92831 2/20 0.58
MAPT P10636 5/20 0.55
RAB9A P51151 4/20 0.55
NPC1 O15118 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ALDH1A1 P00352 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.54
MAPK1 P28482 2/20 0.54
CASP7 P55210 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
GAA P10253 2/20 0.54
POLB P06746 1/20 0.51
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6032002 1.00 MEN1 (0.60) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL1653792 0.85 GPR35 (0.49) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL10225876 0.85 RAB9A (0.58) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL1086052 0.85 KMT2A (0.58) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL3134716 0.85 CTSD (0.51) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL27447187 0.84 ERN1 (0.48) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL5026709 0.83 KAT2B (0.60) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL6300813 0.82 CYP1A2 (0.55) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL4837897 0.82 KMT2A (0.55) MEN1KMT2AKAT2BMAPTRAB9A
SCHEMBL9983928 0.82 KMT2A (0.59) MEN1KMT2AKAT2BMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204445-A2 ASSAYS AND REAGENTS FOR CHARACTERIZATION OF MHCI PEPTIDE BINDING GENENTECH, INC. (US) 2023-07-05 EP claimed
CN-116234813-A Assays and reagents for characterizing MHCI peptide binding 基因泰克公司 2023-06-06 CN claimed
CN-115776987-A Barcoded exchangeable peptide-MHC multimer libraries 瑞佩尔托利免疫医药股份有限公司 2023-03-10 CN claimed
EP-4126923-A2 BARCODABLE EXCHANGEABLE PEPTIDE-MHC MULTIMER LIBRARIES Repertoire Immune Medicines, Inc. (US) 2023-02-08 EP claimed
WO-2021202727-A2 BARCODABLE EXCHANGEABLE PEPTIDE-MHC MULTIMER LIBRARIES Repertoire Immune Medicines, Inc. (US) 2021-10-07 WO claimed
US-9708530-B2 Organic phosphorescent materials and methods for their preparation and use EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-07-18 US claimed
CN-104870603-A Organic phosphorescent materials and methods for their preparation and use EMPIRE TECHNOLOGY DEV LLC 2015-08-26 CN claimed
US-20150131292-A1 ORGANIC PHOSPHORESCENT MATERIALS AND METHODS FOR THEIR PREPARATION AND USE CRESTLINE DIRECT FINANCE, L.P. 2015-05-14 US claimed
WO-2014072874-A1 ORGANIC PHOSPHORESCENT MATERIALS AND METHODS FOR THEIR PREPARATION AND USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (IN) 2014-05-15 WO claimed
WO-2002074928-A2 FUSION PEPTIDES ISOLATABLE BY PHASE TRANSITION CHILKOTI ASHUTOSH (US) 2002-09-26 WO claimed
US-6020480-A Caged NADP and NAD THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-02-01 US claimed
US-5998580-A PROVIDING AN AMINO ACID INCLUDING A PHOTOLABILE MOLECULE AND INCORPORATING THE AMINO ACID INTO A PEPTIDE DURING SYNTHESIS, WHEREIN INCORPORATION OF THE AMINO ACID INTO THE PEPTIDE PRODUCES A PHOTOSENSITIVE PEPTIDE NATIONAL INSTITUTES OF HEALTH, THE 1999-12-07 US claimed
WO-1997013782-A1 PHOTOSENSITIVE CAGED MACROMOLECULES UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) 1997-04-17 WO claimed
EP-0371564-B1 (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA NV (BE) 1995-07-12 EP claimed
US-4946761-A POLYMER CONTAINING CARBOXYL END GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US claimed
EP-0371564-A2 (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-06-06 EP claimed
EP-4423256-A2 SYSTEMS AND METHODS TO IDENTIFY MHC-ASSOCIATED ANTIGENS FOR THERAPEUTIC INTERVENTION Genentech, Inc. (US) 2024-09-04 EP disclosed
US-20240277770-A1 SYSTEMS AND METHODS TO IDENTIFY MHC-ASSOCIATED ANTIGENS FOR THERAPEUTIC INTERVENTION GENENTECH INC (US) 2024-08-22 US disclosed
EP-0254545-A2 Diamine compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-27 EP disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed