SCHEMBL12431397

SCHEMBL12431397

CCOC(=O)c1ccccc1C(=O)c1ccc(N(CC)CC)cc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.72
▸ MEN1 O00255 2/20 0.72
▸ KMT2A Q03164 2/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.72
▸ ALDH1A1 P00352 4/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ POLB P06746 2/20 0.56
▸ GAA P10253 2/20 0.56
▸ TSHR P16473 2/20 0.54
▸ CDC25B P30305 2/20 0.51
▸ CA12 O43570 3/20 0.50
▸ CA1 P00915 3/20 0.50
▸ CA2 P00918 3/20 0.50
▸ CA7 P43166 3/20 0.50
▸ CA9 Q16790 3/20 0.50
▸ CA14 Q9ULX7 3/20 0.50
▸ MAOB P27338 1/20 0.49
▸ MAPT P10636 3/20 0.46
▸ LMNA P02545 2/20 0.46
▸ USP2 O75604 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13301476 0.92 L3MBTL1 (0.72) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301485 0.90 L3MBTL1 (0.69) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301464 0.90 L3MBTL1 (0.69) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL27913467 0.89 MEN1 (0.89) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301475 0.89 L3MBTL1 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301471 0.89 L3MBTL1 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301457 0.89 L3MBTL1 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301483 0.89 SMN1; SMN2 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301467 0.89 L3MBTL1 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13301466 0.89 SMN1; SMN2 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543872-A1 MULTI-PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-04-30 — — EP disclosed
WO-2023247598-A1 MULTI-PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2023-12-28 — — WO disclosed
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties NANOPHASE TECHNOLOGIES CORPORATION (US) 2020-02-11 — — US disclosed
US-7988953-B2 cosmetic; dendritic polyether; sunscreens DSM IP ASSETS B.V. (NL) 2011-08-02 — — US disclosed
US-20080081025-A1 Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers DSM IP ASSETS B.V. (NL) 2008-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties SPIN4, RPS4X, RPS4Y1 SMN1; SMN2 599/4885MEN1 4144/4885KMT2A 2398/4885
US-20080081025-A1 Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers PCNA, MMS19, ERCC4 SMN1; SMN2 2132/4885MEN1 1481/4885KMT2A 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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