Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914883 | 0.86 | CYP1A1 (0.67) | KEAP1CYP2A6NFE2L2AXLKDM4E | |
| Acetic Acid Methyl Ester SCHEMBL27544473 | 0.85 | FLT3 (0.52) | KEAP1CYP2A6NFE2L2AXLKDM4E | |
| SCHEMBL2993745 | 0.83 | KEAP1 (0.52) | KEAP1CYP2A6NFE2L2AXLKDM4E | |
| Tert-Butyl Formate SCHEMBL27601678 | 0.82 | KEAP1 (0.45) | KEAP1CYP2A6NFE2L2AXLKDM4E | |
| SCHEMBL12574858 | 0.78 | KDM4E (0.47) | KEAP1NFE2L2KDM4EALDH1A1LMNA | |
| SCHEMBL75581 | 0.77 | CYP2A6 (0.63) | KEAP1CYP2A6AXLKDM4EALDH1A1 | |
| SCHEMBL29727931 | 0.77 | CYP2A6 (0.63) | KEAP1CYP2A6AXLKDM4EALDH1A1 | |
| SCHEMBL8344266 | 0.74 | CYP2A6 (0.59) | KEAP1CYP2A6AXLKDM4EALDH1A1 | |
| SCHEMBL7669990 | 0.74 | CYP2A6 (0.59) | KEAP1CYP2A6AXLKDM4EALDH1A1 | |
| SCHEMBL11436421 | 0.74 | DAO (0.61) | KDM4EALDH1A1LMNAPDPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112111557-A | Surfactant-free urine analysis quality control liquid | 成都恩普瑞生物工程有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-106995400-B | A kind of compound and its salt and its synthetic method | 湘潭大学 | 2019-08-06 | — | — | CN | claimed |
| EP-3083557-B1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | ATOPIX THERAPEUTICS LTD (GB) | 2017-11-29 | — | — | EP | claimed |
| US-9828359-B2 | Process for the preparation of 3-substituted (indol-1-yl)-acetic acid esters | ATOPIX THERAPEUTICS LIMITED (GB) | 2017-11-28 | — | — | US | claimed |
| US-20170305879-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | ZACH SYSTEM SPA (IT) | 2017-10-26 | — | — | US | claimed |
| EP-3131880-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2017-02-22 | — | — | EP | claimed |
| EP-3083557-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | Atopix Therapeutics Limited (GB) | 2016-10-26 | — | — | EP | claimed |
| WO-2015159233-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-10-22 | — | — | WO | claimed |
| EP-2791129-B1 | PROCESS FOR THE PREPARATION OF (5-FLUORO-2-METHYL-3-QUINOLIN-2-YLMETHYL-INDOL-1-YL)-ACETIC ACID ESTERS | ATOPIX THERAPEUTICS LTD (GB) | 2015-10-07 | — | — | EP | claimed |
| US-9102658-B2 | Process for the preparation of (5-fluoro-2-methyl-3-quinolin-2-ylmethyl-indol-1-y1)-acetic acid esters | ATOPIX THERAPEUTICS LIMITED (GB) | 2015-08-11 | — | — | US | claimed |
| WO-2015092372-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | ATOPIX THERAPEUTICS LIMITED (GB) | 2015-06-25 | — | — | WO | claimed |
| US-20140350264-A1 | Process for the Preparation of (5-Fluoro-2-methyl-3-quinolin-2-ylmethyl-indol-1-yl)-Acetic Acid Esters | OXAGEN LIMITED (GB) | 2014-11-27 | — | — | US | claimed |
| EP-2791129-A1 | PROCESS FOR THE PREPARATION OF (5-FLUORO-2-METHYL-3-QUINOLIN-2-YLMETHYL-INDOL-1-YL)-ACETIC ACID ESTERS | Atopix Therapeutics Limited (GB) | 2014-10-22 | — | — | EP | claimed |
| WO-2013088108-A1 | PROCESS FOR THE PREPARATION OF (5-FLUORO-2-METHYL-3-QUINOLIN-2-YLMETHYL-INDOL-1-YL)-ACETIC ACID ESTERS | OXAGEN LIMITED (GB) | 2013-06-20 | — | — | WO | claimed |
| EP-4710923-A2 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-12522582-B2 | Antiviral indolinyl compounds and uses thereof | GILEAD SCIENCES, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| EP-3612030-B1 | INDOLE AHR INHIBITORS AND USES THEREOF | IKENA ONCOLOGY INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-4021448-A | ANTISECRETORY AND ANTIULCER ACTIVITIES | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
| US-3956267-A | Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350264-A1 | Process for the Preparation of (5-Fluoro-2-methyl-3-quinolin-2-ylmethyl-indol-1-yl)-Acetic Acid Esters | ADH1C, ALDH7A1, AKR1C1 | KEAP1 1211/4885CYP2A6 23/4885NFE2L2 1885/4885 |
| US-20170305879-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | IDO1, IDO2, SI | KEAP1 2738/4885CYP2A6 1079/4885NFE2L2 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.