SCHEMBL12433155

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12431984	0.87	POLB (0.60)	MRGPRX4L3MBTL1POLBHSD17B10TDP1
	SCHEMBL2317454	0.87	RXRA (0.61)	MRGPRX4HDAC1HDAC8HDAC6L3MBTL1
	SCHEMBL12432158	0.86	RXRA (0.57)	MRGPRX4NR4A2L3MBTL1POLBHSD17B10
	Hydrochloric Acid SCHEMBL16143333	0.85	RXRA (0.60)	MRGPRX4HDAC1HDAC8HDAC6L3MBTL1
	SCHEMBL12433003	0.85	RXRA (0.61)	MRGPRX4NR4A2L3MBTL1POLBHSD17B10
	SCHEMBL14906965	0.84	MRGPRX4 (1.00)	MRGPRX4HDAC1HDAC8HDAC6NR4A2
	SCHEMBL15673277	0.84	RXRA (0.62)	MRGPRX4HDAC1HDAC8HDAC6L3MBTL1
	SCHEMBL10323084	0.83	KDM4E (0.64)	MRGPRX4HDAC1HDAC8HDAC6SMPD1
	SCHEMBL6723445	0.83	RXRA (0.60)	MRGPRX4NR4A2L3MBTL1POLBHSD17B10
	SCHEMBL13339376	0.83	SMN1; SMN2 (0.57)	MRGPRX4L3MBTL1POLBHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.