Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | RXRB | P28702 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433001 | 0.88 | RXRA (0.56) | RXRARXRBRXRGL3MBTL1POLB | |
| SCHEMBL12431984 | 0.85 | POLB (0.60) | RXRAL3MBTL1RAB9APOLBHSD17B10 | |
| SCHEMBL2317454 | 0.84 | RXRA (0.61) | RXRAL3MBTL1RAB9APOLBHSD17B10 | |
| SCHEMBL12432158 | 0.83 | RXRA (0.57) | RXRANR4A2L3MBTL1POLBHSD17B10 | |
| SCHEMBL12433155 | 0.83 | MRGPRX4 (0.73) | RXRANR4A2L3MBTL1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL16143333 | 0.83 | RXRA (0.60) | RXRAL3MBTL1RAB9APOLBHSD17B10 | |
| SCHEMBL5014148 | 0.82 | RXRA (0.62) | RXRANR4A2RXRBNR4A1NR4A3 | |
| SCHEMBL4272450 | 0.82 | RXRA (0.62) | RXRANR4A2RXRBNR4A1NR4A3 | |
| SCHEMBL6723656 | 0.82 | RXRA (0.64) | RXRANR4A2RXRBNR4A1NR4A3 | |
| SCHEMBL15673277 | 0.82 | RXRA (0.62) | RXRAL3MBTL1RAB9APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |