SCHEMBL12433585

SCHEMBL12433585

Cc1ccc2c(c1)oc1cc(C)c3ccccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
CDC25A P30304 1/20 0.39
CDC25C P30307 1/20 0.39
MAOB P27338 2/20 0.39
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
GAA P10253 1/20 0.38
POLB P06746 2/20 0.38
CYP1A2 P05177 4/20 0.38
AHR P35869 1/20 0.37
KIF11 P52732 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.36
CYP2A6 P11509 1/20 0.36
MAPT P10636 3/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15725991 0.86 KDM4E (0.43) MAOAALDH1A1HPGDCYP1A2AHR
SCHEMBL14134120 0.85 MAOA (0.49) MAOAALDH1A1HPGDGAACYP1A2
SCHEMBL12433599 0.85 CYP2A6 (0.40) MAOACDC25ACDC25CMAOBALDH1A1
SCHEMBL20208885 0.84 MAOA (0.51) MAOAALDH1A1HPGDPOLBCYP1A2
SCHEMBL12433584 0.83 CYP1A2 (0.46) MAOAALDH1A1HPGDGAACYP1A2
SCHEMBL13508895 0.80 MAOB (0.42) MAOACDC25ACDC25CMAOBALDH1A1
SCHEMBL13562170 0.80 HPRT1 (0.45) MAOAMAOBALDH1A1HPGDCYP1A2
SCHEMBL10109875 0.79 L3MBTL1 (0.47) MAOAMAOBALDH1A1HPGDGAA
SCHEMBL18810722 0.79 DYRK1A (0.42) MAOAALDH1A1POLBCYP1A2AHR
SCHEMBL11992359 0.79 MAPT (0.41) ALDH1A1HPGDCYP1A2AHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed
US-20200055822-A1 MATERIALS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-02-20 US disclosed
EP-2732479-B1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-11 EP disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
WO-2013007348-A1 COMPOSITIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-17 WO disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271989-A1 METAL COMPLEXES AP3M1, AP1M1, AP2M1 MAOA 2360/4885CDC25A 4160/4885CDC25C 3363/4885
US-20200055822-A1 MATERIALS FOR ORGANIC ELECTRONIC DEVICES PNMT, DDT, TYR MAOA 24/4885CDC25A 3550/4885CDC25C 3639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.