Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14866930 | 0.86 | CYP3A4 (0.82) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL10031574 | 0.86 | MME (0.65) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL10283303 | 0.86 | MME (0.65) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL1516159 | 0.86 | MME (0.65) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL23879676 | 0.84 | MME (0.63) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| Benzene SCHEMBL10805389 | 0.84 | MME (0.63) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL17780637 | 0.84 | MME (0.63) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL18769016 | 0.84 | MME (0.63) | MMEALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL5411548 | 0.84 | LMNA (0.49) | MMEALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL8760 | 0.83 | KMT2A (0.67) | MMEALDH1A1CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759582-B2 | Process for the preparation of lacosamide | NATCO PHARMA LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-20130095535-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | MEDICHEM, S.A. (ES) | 2013-04-18 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
| WO-2011092672-A2 | PROCESSES FOR REDUCING IMPURITIES IN LACOSAMIDE | RANBAXY LABORATORIES LIMITED (IN) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CA3, CACNA1A, CA2 | MME 53/4885ALDH1A1 1559/4885CYP3A4 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.