Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196371 | 0.89 | TSHR (0.53) | TSHRKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL15151735 | 0.79 | MAPT (0.43) | KMT2AMEN1MAPTL3MBTL1ATM | |
| SCHEMBL16502112 | 0.78 | MAPT (0.61) | KMT2AMEN1MAPTL3MBTL1ATM | |
| SCHEMBL10053938 | 0.78 | ACHE (0.58) | KMT2AMEN1MAPTL3MBTL1RAB9A | |
| SCHEMBL14526048 | 0.77 | ACHE (0.62) | TSHRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20005637 | 0.76 | SMN1; SMN2 (0.54) | TSHRKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL1010950 | 0.76 | THRB (0.42) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL14405204 | 0.76 | THRB (0.42) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL29200144 | 0.75 | ELANE (0.41) | TSHRKMT2AMEN1MAPTATM | |
| SCHEMBL6608551 | 0.75 | KMT2A (0.53) | TSHRKMT2AMEN1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092128-A1 | SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |