SCHEMBL1010950

SCHEMBL1010950

CCCCCCCCCCCCCCCCCCOc1cc(C)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.42
THRA P10827 2/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ESR1 P03372 2/20 0.41
TLR8 Q9NR97 1/20 0.41
MEN1 O00255 1/20 0.40
NR1I2 O75469 1/20 0.40
LMNA P02545 1/20 0.40
CHRM2 P08172 1/20 0.40
CYP3A4 P08684 1/20 0.40
ADRA2A P08913 1/20 0.40
OPRK1 P41145 1/20 0.40
HTR2B P41595 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
NR5A1 Q13285 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14405204 1.00 THRB (0.42) THRBTHRAMAPTALDH1A1GAA
SCHEMBL15151735 0.92 MAPT (0.43) THRBTHRAMAPTALDH1A1GAA
SCHEMBL13933173 0.91 MAPT (0.43) THRBTHRAMAPTALDH1A1GAA
SCHEMBL13933174 0.91 MAPT (0.43) THRBTHRAMAPTALDH1A1GAA
SCHEMBL16087725 0.89 ACHE (0.52) MAPTHTR2B
SCHEMBL12432397 0.89 ACHE (0.52)
SCHEMBL4430056 0.87 THRB (0.38) THRBTHRAMAPTALDH1A1GAA
SCHEMBL12433117 0.86 ACHE (0.54) MAPT
SCHEMBL17589108 0.84 THRB (0.42) THRBTHRAMAPTALDH1A1GAA
SCHEMBL5268487 0.82 THRA (0.44) THRBTHRANR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717239-B Precipitation accelerator and precipitation method using the same 味之素株式会社 2024-12-24 CN disclosed
EP-3263579-B1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO KK (JP) 2022-11-30 EP disclosed
EP-4049991-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2022-08-31 EP disclosed
US-10464966-B2 Precipitation promoter and precipitation method in which same is used AJINOMOTO CO., INC. (JP) 2019-11-05 US disclosed
EP-3263579-A1 PRECIPITATION ACCELERATOR AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2018-01-03 EP disclosed
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2017-11-09 US disclosed
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2017-11-09 US disclosed
EP-1426101-B1 COMPATIBLE-MULTIPHASE ORGANIC SOLVENT SYSTEM JAPAN SCIENCE & TECH AGENCY (JP) 2011-01-05 EP disclosed
US-20100184952-A1 METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE AJINOMOTO CO., INC (JP) 2010-07-22 US disclosed
EP-2181983-A1 METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE Ajinomoto Co., Inc. (JP) 2010-05-05 EP disclosed
EP-1426101-A1 COMPATIBLE-MULTIPHASE ORGANIC SOLVENT SYSTEM Japan Science and Technology Agency (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED SP1, MED25, CTCF THRB 3519/4885THRA 4084/4885MAPT 1874/4885
US-10464966-B2 Precipitation promoter and precipitation method in which same is used SP1, MED25, CTCF THRB 3519/4885THRA 4084/4885MAPT 1874/4885
US-20100184952-A1 METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE DDC, DNPEP, DBF4 THRB 2265/4885THRA 3221/4885MAPT 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.