Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11911982 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4ENFKB1POLBMAPT | |
| SCHEMBL12344320 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4ENFKB1POLBMAPT | |
| SCHEMBL14266502 | 0.89 | NFKB1 (0.36) | ALDH1A1KDM4ENFKB1POLBMAPT | |
| SCHEMBL25015671 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KDM4ENFKB1POLBMAPT | |
| SCHEMBL801285 | 0.83 | ALDH1A1 (0.33) | ALDH1A1KDM4ENFKB1POLBMAPT | |
| SCHEMBL801237 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KDM4ENFKB1MAPTTHRB | |
| SCHEMBL801063 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KDM4ENFKB1MAPTTHRB | |
| SCHEMBL18612347 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ENFKB1MAPTTHRB | |
| SCHEMBL7940721 | 0.77 | DPP4 (0.35) | ALDH1A1POLBMAPTSMN1; SMN2DPP4 | |
| SCHEMBL12207195 | 0.77 | DPP4 (0.35) | ALDH1A1NFKB1POLBTHPOBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834408-B2 | Compounds for the treatment of SARS | PURDUE RESEARCH FOUNDATION (US) | 2023-12-05 | — | — | US | disclosed |
| US-20110178092-A1 | HIV-1 Protease Inhibitors | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178092-A1 | HIV-1 Protease Inhibitors | SERPINB1, PRSS1, TMPRSS4 | ALDH1A1 2716/4885KDM4E 1140/4885NFKB1 2210/4885 |
| US-11834408-B2 | Compounds for the treatment of SARS | ACE2, SARS1, ACE | ALDH1A1 2923/4885KDM4E 4049/4885NFKB1 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.