Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854747 | 0.81 | SRD5A2 (0.41) | SRD5A2ESR1AR | |
| SCHEMBL11854755 | 0.81 | SRD5A2 (0.41) | SRD5A2ESR1AR | |
| SCHEMBL12446650 | 0.76 | SRD5A2 (0.39) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11863792 | 0.73 | SRD5A2 (0.40) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11863797 | 0.73 | SRD5A2 (0.40) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11861828 | 0.70 | SHBG (0.58) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11861831 | 0.70 | SHBG (0.58) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11518021 | 0.69 | ESR1 (0.58) | SRD5A2LMNAESR1AR | |
| SCHEMBL11864782 | 0.68 | PGR (0.45) | SRD5A2LMNAESR1PGRAR | |
| SCHEMBL11864787 | 0.68 | PGR (0.45) | SRD5A2LMNAESR1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354150-A1 | Process for the preparation of gestodene | LABORATOIRE THERAMEX (MC) | 2011-08-10 | — | — | EP | disclosed |