Sugi Predict

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SCHEMBL12435751

SCHEMBL12435751

c1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc(-c5cccc6ccccc56)nc4)c4ccccc34)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.41
▸ CA9 Q16790 2/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CYP11B1 P15538 3/20 0.41
▸ CYP11B2 P19099 3/20 0.41
▸ ATR Q13535 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17680015 0.94 CYP11B1 (0.41) CA12CA9CA1CA2CYP11B1
SCHEMBL17680010 0.93 CYP11B1 (0.43) CA12CA9CA1CA2CYP11B1
SCHEMBL12436888 0.93 CYP11B1 (0.43) CA12CA9CA1CA2CYP11B1
SCHEMBL21249206 0.92 CA12 (0.40) CA12CA9CA1CA2CYP11B1
SCHEMBL12435976 0.91 CYP11B1 (0.44) CYP11B1CYP11B2ATRMEN1KMT2A
SCHEMBL21249210 0.91 CA12 (0.40) CA12CA9CA1CA2CYP11B1
SCHEMBL23094374 0.90 MEN1 (0.39) CA12CA9CA1CA2CYP11B1
SCHEMBL9613088 0.90 CA12 (0.40) CA12CA9CA1CA2CYP11B1
SCHEMBL21467566 0.89 TNF (0.44) CA12CA9CA1CA2CYP11B1
SCHEMBL23619793 0.89 MCL1 (0.42) CA12CA9CA1CA2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10950803-B2 Compounds and uses in devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-16 — — US disclosed
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 — — US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 — — US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 — — US disclosed
US-20160104847-A1 NOVEL COMPOUNDS AND USES IN DEVICES UNIVERSAL DISPLAY CORPORATION 2016-04-14 — — US disclosed
WO-2011037380-A9 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2011-08-04 — — WO disclosed
WO-2011037380-A2 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2011-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160104847-A1 NOVEL COMPOUNDS AND USES IN DEVICES TERT, UACA, TXN CA12 725/4885CA9 695/4885CA1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.