Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436013 | 0.80 | KMT2A (0.58) | KMT2APOLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12436008 | 0.76 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL12435943 | 0.75 | NPC1 (0.58) | KMT2APOLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12436015 | 0.73 | LMNA (0.62) | KMT2ASMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL12436017 | 0.71 | SMN1; SMN2 (0.63) | KMT2ASMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL12435989 | 0.69 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL12512678 | 0.68 | GAA (0.40) | KMT2APOLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2219490 | 0.66 | SMN1; SMN2 (0.59) | KMT2APOLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12435963 | 0.65 | MAPT (0.58) | KMT2APOLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12436031 | 0.65 | MAPK1 (0.57) | KMT2APOLBSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Academy of Medical Science (CN) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | CUL3, APOBEC3G, BRPF3 | KMT2A 964/4885POLB 1111/4885SMN1; SMN2 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.