Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435943 | 0.81 | NPC1 (0.58) | KMT2AALDH1A1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL12436010 | 0.80 | KMT2A (0.43) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 | |
| SCHEMBL12435989 | 0.76 | SMN1; SMN2 (0.58) | KMT2AALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL12436015 | 0.76 | LMNA (0.62) | KMT2AALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL12436017 | 0.73 | SMN1; SMN2 (0.63) | KMT2AALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL328330 | 0.73 | ALDH1A1 (0.74) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 | |
| SCHEMBL24274737 | 0.73 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 | |
| SCHEMBL7824834 | 0.72 | ALDH1A1 (0.78) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 | |
| SCHEMBL5449670 | 0.72 | ALDH1A1 (0.73) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 | |
| Sulfadimethoxine SCHEMBL29363944 | 0.71 | LMNA (1.00) | KMT2AALDH1A1SMN1; SMN2HTTAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Academy of Medical Science (CN) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | CUL3, APOBEC3G, BRPF3 | KMT2A 964/4885ALDH1A1 2851/4885SMN1; SMN2 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.