Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12857809 | 0.93 | OPRM1 (0.49) | OPRM1OPRL1CA4LTA4HTRPA1 | |
| SCHEMBL18288047 | 0.92 | CA1 (0.48) | OPRM1OPRL1CA12CA1CA2 | |
| SCHEMBL12957015 | 0.86 | OPRM1 (0.40) | OPRM1OPRL1CA4OPRD1OPRK1 | |
| SCHEMBL12857816 | 0.85 | ACHE (0.56) | OPRM1OPRL1CA12CA1CA2 | |
| SCHEMBL12857675 | 0.85 | ACHE (0.56) | OPRM1OPRL1CA12CA1CA2 | |
| SCHEMBL27009310 | 0.84 | KDM1A (0.47) | OPRM1OPRL1CA4OPRD1OPRK1 | |
| SCHEMBL12858074 | 0.84 | ACHE (0.46) | OPRM1OPRL1MAOBMAOABACE1 | |
| SCHEMBL11616948 | 0.82 | CYP26A1 (0.39) | OPRM1OPRL1OPRK1MAOBMAOA | |
| SCHEMBL12857680 | 0.81 | ACHE (0.50) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL21709933 | 0.81 | CYP1A1 (0.50) | OPRM1OPRL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304316-B1 | PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS | DAIKIN IND LTD (JP) | 2011-08-10 | — | — | EP | disclosed |